Apobec Enzymes

Apobec Enzymes by F. Nina Papavasiliou delivers a compelling, up-to-date exploration of APOBEC family proteins—the cellular editors that shape immunity, viral defense, and cancer evolution. Clear, authoritative, and richly contextualized, this volume immediately draws in molecular biologists, immunologists, clinicians, and advanced students across North America, Europe, and Asia seeking a rigorous yet accessible synthesis.

Beginning with the biochemical mechanisms of cytidine deamination, the text moves smoothly to structural insights, genomic consequences, and the dual role of APOBEC enzymes in antiviral protection and oncogenic mutagenesis. Papavasiliou combines landmark discoveries with recent advances in sequencing and structural biology to explain how APOBEC activity is regulated, misregulated, and exploited by pathogens and tumors. Case studies highlight implications for viral latency, antibody diversification, and therapeutic resistance—content highly relevant to researchers and translational teams in Boston, London, Berlin, and beyond.

Readers will gain practical understanding of experimental approaches, interpretive frameworks for mutation signatures, and the clinical significance of APOBEC-driven mutagenesis—information that enhances grant proposals, laboratory strategy, and patient-centered research. The writing balances technical precision with engaging narrative, making complex topics approachable without sacrificing depth.

For anyone investigating genome dynamics, host–pathogen interactions, or cancer genomics, Apobec Enzymes is an indispensable reference. Secure your copy today from leading bookstores and online retailers worldwide to stay at the forefront of APOBEC research and its translational potential.

Note: eBooks do not include supplementary materials such as CDs, access codes, etc.