Why the Dose Matters 1st Edition

Why the Dose Matters (1st Edition) by Urs A. Boelsterli is an essential read for anyone working at the intersection of toxicology, pharmacology, and drug safety. This authoritative volume unpacks the fundamental principle that dose—not just exposure—drives biological effect, offering clear explanations of dose-response relationships, metabolic pathways, and risk thresholds that shape clinical and regulatory decisions worldwide.

Engaging and sharply focused, the book translates complex science into practical insight. Through case-based discussions and mechanistic analysis, it illuminates why small changes in dose can produce dramatic shifts in outcome, covering topics from hepatic toxicity and reactive metabolites to inter-individual variability and environmental exposure. Written for clinicians, toxicologists, pharmacologists, researchers, and advanced students, the text bridges laboratory data and real-world implications for patient safety and public health.

Readers will gain actionable knowledge to better interpret dose-response data, assess safety margins, and design safer therapeutics. Its clear organization and evidence-driven approach make it a go-to reference for risk assessment, drug development, and clinical decision-making in Europe, North America, and beyond.

If you require a rigorous, readable guide that clarifies why dose is central to safety and efficacy, Why the Dose Matters is an indispensable addition to your professional library. Order your copy today to deepen your understanding of dose-related toxicity and improve outcomes in research, clinical practice, and regulatory work.

Note: eBooks do not include supplementary materials such as CDs, access codes, etc.