Osmolytes and Intrinsically Disordered Proteins: From Functional Regulation to Disease Pathogenesis

Osmolytes and Intrinsically Disordered Proteins: From Functional Regulation to Disease Pathogenesis by Tanveer Ali Dar, Laishram Rajendrakumar Singh, and Vladimir N. Uversky is a definitive, modern exploration of how small organic solutes—osmolytes—shape the behavior of intrinsically disordered proteins (IDPs) and influence health and disease.

Begin with a compelling overview that places osmolytes and IDPs at the cutting edge of molecular biology. This book synthesizes current research on protein folding dynamics, conformational ensembles, and the regulatory roles osmolytes play in stabilizing or modulating IDP function. Clear, evidence-based chapters bridge basic biophysics and translational implications.

Dive deeper into techniques and findings: detailed coverage of spectroscopy, molecular simulations, cellular assays, and biophysical models that reveal how osmolytes impact phase separation, aggregation, and protein–protein interactions. Case studies link these mechanisms to neurodegenerative disorders, cancer biology, and metabolic disease, making the content highly relevant for researchers and clinicians alike.

Imagine applying these insights directly to your work—whether you’re a structural biologist, pharmacologist, graduate student, or industry scientist. The book delivers practical perspectives on targeting IDP behavior, designing experiments, and interpreting complex datasets, empowering you to advance research and therapeutic strategies.

Ideal for audiences across North America, Europe, Asia, and beyond, this comprehensive volume is both a scholarly reference and a hands-on guide. Enhance your library with this authoritative resource—order your copy today to stay at the forefront of protein science and disease pathogenesis.

Note: eBooks do not include supplementary materials such as CDs, access codes, etc.