Resistance to Anti-CD20 Antibodies and Approaches for Their Reversal 1st Edition

Resistance to Anti-CD20 Antibodies and Approaches for Their Reversal, 1st Edition by William Chi Shing Cho is an indispensable, up-to-date resource for clinicians, researchers and pharmaceutical scientists confronting the growing challenge of anti-CD20 therapeutic resistance. This clear, compelling volume opens with concise explanations of the molecular and cellular mechanisms underlying resistance to agents such as rituximab and next-generation anti-CD20 antibodies—making complex immunology accessible to busy specialists.

Inside, you’ll find detailed discussion of biomarkers, Fc-mediated effector function, complement pathways, antigen modulation, and tumor microenvironment factors, paired with translational strategies to overcome resistance. Case-driven insights and practical frameworks help you interpret laboratory data, design rational combination approaches, and prioritize patients for targeted interventions. The book balances rigorous science with clinical applicability, helping hematologists, oncologists, neurologists and translational researchers bridge bench-to-bedside gaps.

Whether you practice in North America, Europe, Asia-Pacific or beyond, this edition equips you with actionable knowledge for improving trial design, optimizing dosing and sequencing, and anticipating resistance patterns in lymphoma, chronic lymphocytic leukemia and autoimmune indications. Written in a professional yet engaging tone, William Chi Shing Cho provides both the evidence base and strategic direction needed to inform patient-focused decision-making.

Essential for libraries in academic centers and clinical departments, this volume stands as a timely reference for anyone involved in B-cell–directed therapies. Add this authoritative guide to your collection to stay at the forefront of anti-CD20 resistance research and its reversal strategies.

Note: eBooks do not include supplementary materials such as CDs, access codes, etc.