Design and Analysis of Pragmatic Trials 1st Edition

Design and Analysis of Pragmatic Trials, 1st Edition by Song Zhang, Chul Ahn, and Hong Zhu is an essential guide for researchers, clinicians, and biostatisticians who design and analyze clinical studies in real-world settings. Clear, practical, and authoritative, this book zeroes in on the methods that make pragmatic trials reliable, scalable, and relevant for everyday healthcare decisions.

Discover a balanced blend of theory and practice: the authors translate modern statistical principles into actionable strategies for trial design, sample-size determination, randomization, handling missing data, and robust analysis approaches that preserve external validity. Emphasizing real-world applicability, the text addresses heterogeneity across patient populations, cluster- and registry-based designs, and considerations for health-system implementation and policy translation.

Whether you’re leading a multicenter study in North America, evaluating interventions across Europe, or running pragmatic evaluations in Asia and beyond, this volume offers globally relevant guidance. Annotated examples and case-focused explanations help you anticipate practical challenges and interpret results that matter to clinicians, regulators, and payers.

Ideal for trialists, applied statisticians, public-health researchers, and advanced students, this edition equips you to design studies that answer real clinical questions with statistical rigor. It enhances your ability to move from protocol to practice—improving decision-making at the point of care.

Add Design and Analysis of Pragmatic Trials to your professional library to strengthen your trial methodology toolkit and deliver evidence that better reflects everyday clinical reality. Order now to bring robust, real-world research methods into your next pragmatic study.

Note: eBooks do not include supplementary materials such as CDs, access codes, etc.