Concepts and Models for Drug Permeability Studies 2nd Edition

Concepts and Models for Drug Permeability Studies, 2nd Edition by Bruno Sarmento, Catarina Leite Pereira, and José Das Neves is an essential, up-to-date resource for scientists and students confronting the critical challenge of predicting and optimizing drug absorption. This revised edition brings clarity to complex permeability science, blending theoretical foundations with practical approaches used across academia and industry worldwide.

Discover clear explanations of core principles—membrane transport, physicochemical determinants of absorption, and the interplay between formulation and biological barriers—alongside an overview of commonly used experimental and computational models. Readers will find guidance on in vitro tools (including Caco-2 and PAMPA models), ex vivo approaches, translational strategies, and in silico predictions that support robust pharmacokinetic understanding and regulatory-ready dossiers.

Written by internationally recognized experts, the book translates advanced science into actionable insight for formulation scientists, pharmacologists, regulatory professionals, and graduate students. Practical examples and comparative discussions help teams accelerate lead selection, optimize oral bioavailability, and reduce downstream development risk in Europe, North America, Asia, and emerging markets.

Whether you’re building a permeability testing program, teaching a graduate course, or refining a formulation strategy, this edition equips you with the concepts and models needed to make informed decisions. Add this authoritative title to your professional library and strengthen your ability to turn permeability data into reliable development outcomes.

Note: eBooks do not include supplementary materials such as CDs, access codes, etc.